{"ATC Code":"N - Nervous system","Abbreviation":"Ether","Aliases":["ether","Ethyl ether","Pronarcol","Diethyl oxide","Aether","Diethylether","Solvent ether","3-Oxapentane","Anesthesia ether","Diethylaether"],"Boiling Point":"94.3 °","CAS":"60-29-7","ChEBI":"CHEBI:35702","ChEMBL":"CHEMBL16264","ChemicalClasses":[],"Chirality":"achiral","Color/Form":"Colorless, volatile, mobile liquid","Decomposition":"When heated to decomposition it emits acrid smoke and irritating fumes.","Density":"0.714 at 68 °F (USCG, 1999) - Less dense than water; will float g/cm\u003csup\u003e3\u003c/sup\u003e","Dosing Info":[],"Drug Warnings":"Main contraindications to ether anesthesia are acute and chronic respiratory diseases and advanced renal disease.","DrugClasses":[],"EINECS":"200-467-2","European Community (EC) Number":"200-467-2","Flash Point":"-49 °F (NTP, 1992)","HMDB ID":"HMDB0062326","HeavyAtomCount":5,"IUPACName":"ethoxyethane","InChI":"InChI=1S/C4H10O/c1-3-5-4-2/h3-4H2,1-2H3","InChIKey":"RTZKZFJDLAIYFH-UHFFFAOYSA-N","MeSH Pharmacological Classification":"Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant and Hackh\u0026apos;s Chemical Dictionary, 5th ed) (See all compounds classified as Solvents.)","Melting Point":"-177.3 °F (NTP, 1992)","MolecularFormula":"C\u003csub\u003e4\u003c/sub\u003eH\u003csub\u003e10\u003c/sub\u003eO","MolecularWeight":"74.12 g/mol","Odor":"Sweetish, pungent odor","Physical Description":"Diethyl ether appears as a clear colorless liquid with an anesthetic odor. Flash point -49 °F. Less dense than water and slightly soluble in water. Hence floats on water. Vapors are heavier than air. Used as a solvent and to make other chemicals.","PrevSalts":[],"PubChemId":3283,"Record Description":["Diethyl ether appears as a clear colorless liquid with an anesthetic odor. Flash point -49 °F. Less dense than water and slightly soluble in water. Hence floats on water. Vapors are heavier than air. Used as a solvent and to make other chemicals.","Diethyl ether is an ether in which the oxygen atom is linked to two ethyl groups. It has a role as an inhalation anaesthetic, a non-polar solvent and a refrigerant. It is a volatile organic compound and an ether.","Diethyl Ether has been reported in Basella alba and Acca sellowiana with data available.","Ether is an organic compound in which two carbon atoms are linked through an oxygen atom (C-O-C).  An ether may be a product of the condensation of alcohols.  Ether also refers loosely to diethyl-ether, a colorless, volatile, highly inflammable liquid used in industry and biomedical research, and historically important as an anesthetic agent.  In vivo, ether acts similarly to alcohol and chloroform, but its stimulant action on the heart is much more marked.  Ether is a rapidly diffusible stimulant. (NCI04)","ETHER is a small molecule drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.","Diethyl ether, also known as ether and ethoxyethane, is a clear, colorless, and highly flammable liquid with a low boiling point and a characteristic odor. It is the most common member of a class of chemical compounds known generically as ethers. Diethyl ether is used as a common solvent and has been used as a general anesthetic. It can also be found in recreational drug use. (L1660)","A mobile, very volatile, highly flammable liquid used as an inhalation anesthetic and as a solvent for waxes, fats, oils, perfumes, alkaloids, and gums. It is mildly irritating to skin and mucous membranes.","See also: Alcohols, C14-26, ethoxylated (annotation moved to).","Diethyl ether is an ether in which the oxygen atom is linked to two ethyl groups. It has a role as an inhalation anaesthetic, a non-polar solvent and a refrigerant. It is a volatile organic compound and an ether."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Diethyl ether","Name":"Diethyl ether","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q202218","Name":"Diethyl ether","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB13598","Name":"Diethyl ether","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/3283","Name":"Diethyl ether","Sub":false}]},{"Name":"ChemSpider","Urls":[{"Link":"https://www.chemspider.com/Chemical-Structure.3168.html","Name":"Diethyl ether","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL16264","Name":"Diethyl ether","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:35702","Name":"Diethyl ether","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=60-29-7","Name":"Diethyl ether","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0062326","Name":"Diethyl ether","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/D01772","Name":"Diethyl ether","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/0F5N573A2Y","Name":"Diethyl ether","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021720","Name":"Diethyl ether","Sub":false}]}],"Reported Fatal Dose":"Blood level: ... Lethal= 1400-1890 ug/mL","SMILES":"CCOCC","Solubility":"greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)","Stability/Shelf Life":"It is slowly oxidized by action of air, moisture, and light, with formation of peroxides.","StoreUNII":["0F5N573A2Y"],"StructureBase64":"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","Taste":"Burning and sweet taste","Therapeutic Uses":"Anesthetics, Inhalation; Solvents","Title":"Diethyl ether","UNII":"0F5N573A2Y","Wikidata":"Q202218","XLogP":0.9}